I personally liked this series as well.
If you like romantic comedies, as well as Slice of Life high school drama's, then you'll like Kare Kano.
I would however, recommend the Manga over the Anime. Simply because only the anime covers only the first 7 out of 21 volumes that the manga has.
This series deals with some pretty heavy subject matter, like suicide, child abuse, abandonment, pre-marital sexual relations and the risks involved with that (IE Pregnancy). It also touches on peer pressure and bullying. It does all that with out losing sight of the fact that this series is a comedy as well, and a funny one at that.
Go read the manga, its English adaptation is published by Tokyo Pop, and they did an excellent job and will keep you riveted till the end (And the ending is one of those touchy feely warm feeling in your chest kind of endings)