The very first time I saw Ranma 1/2, I was totally lost. I love that. "WTF is going on?!" People turning into animals randomly, and the romantic comedy elements are good laughs.
Funny, last time I was on a plane, I was feeling otaku-ish for watching anime on my laptop, then I looked across the aisle and see this dude older than me reading a Ranma 1/2 manga! Awesome.