I just finished a comedy anime called "Bokusatsu Tenshi Dokuro-Chan", and while its jokes are wrong on so many levels, I can't help but think it's just about the funniest anime I've seen. Never in an anime have I laughed out loud so much, or so uncontrollably.
The basic concept is that there's an angel named Dokuro who lives with some random school boy whose name eludes me, but she constantly beats the tar out of him with a spiked mace. She's also protecting him from other "angels" who want to kill him because in the future he's supposed to discover a technology that stops girls from growing after age 12.
I'd give it a 9/10, but heed my warning, it is not for everyone, and is definately for mature audiences. Tons of blood, and innapropriate jokes abound.