Welcome to the N.H.K. revolves around the lives of several young-adults all living in or around the city of Tokyo. Many different lifestyles are shown though most of the time the story focuses on the concepts of being a hikikomori, anime otaku, and having most of the characters experience intense feelings of depression and loneliness.
The main protagonist is Tatsuhiro Satō, a university dropout entering his fourth year of unemployment. He leads a reclusive life as a hikikomori, ultimately coming to the bizarre conclusion that this happened due to some sort of conspiracy. One day just when his life seems entirely unchanging, he meets Misaki Nakahara, a mysterious girl who claims to be able to cure Tatsuhiro of his hikikomori ways. She presents him with a contract basically outlining that once a day they would meet in the evening in a local park where Misaki would lecture to Tatsuhiro in an effort to rid him of his lifestyle. During these outings, many subjects are discussed, though they almost always pertain in some way to psychology or psychoanalysis.