I have to hold a special place for Cartoon Network in my heart because they do a reasonable job of taking animes that would work with kids and placing them on-air. Really, if it was not for them, it would not be as easy for us to procure Anime and Manga.
However, I think that it's obviously overrated. All of my favorite animes I have procured (originally) via the BitTorrent network. And yes, I said Anime-S, because I really can't sit down and think of an ABSOLUTE FAVORITE.
Love Hina and Ah! Megisama (The OVA) always hit me deep a few years ago, and I watched them obsessively. As well, things like Onegai Teacher, Golden Boy, Chobits, Genshiken, Mai HiME, Elfen Lied... yeah, I could sit here for a year trying to list this stuff out.