ARAVA is suggested in adults for the treatment of active rheumatoid arthritis (RA):
To reduce symptoms and signs
to inhibit structural damage as confirmed by X-ray erosions and joint space thinning
to enhance bodily function
Simply take this medication only as instructed by your physician. Do not take more of it, don't take it more frequently, and do not take it for a lengthy period than your doctor ordered.
The dosage of the medication may be different for different individuals. Follow your doctor's orders or the instructions on the tag. The following information includes only the average amounts of this medicine. If your dose is different, don't change it unless your doctor tells you to accomplish that.
The number of medication that you take depends on the power of the medication. Also, the amount of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical issue that you are utilizing the medicine.
For oral dosage form (tablets):
For rheumatoid arthritis:
AdultsAt first, 100 milligrams (mg) once a day for three times, then 20 mg one time a day. Your personal doctor may adjust the dosage as required.
ChildrenUse and dose has to be decided by your physician.
In case you miss a dose of the medication, take it as soon as you can. But when it is nearly time for your next dose, omit the missed dosage and go back to your regular dosing timetable. Do not double doses.
It is very essential your physician monitor your progress at regular visits to make sure that this medication is working correctly. Blood tests may be necessary to check for unwanted effects.
Using this medicine while you are pregnant can hurt your unborn child. Use an effective form of birth control to avoid becoming pregnant. If you believe you have become pregnant while using the medication, tell your doctor immediately.
Leflunomide may also lead to birth defects if the dad is using it when his sexual partner becomes pregnant. Men taking leflunomide ought to use condoms as a type of contraception during sexual activity. A guy meaning to father a kid should quit using this medicine and seek advice from his doctor immediately.
Serious skin reactions can happen with this medicine. Stop using this medicine and always check with your doctor right away if you've got some of the following symptoms while taking this medicine: blistering, peeling, or loosening of the skin; chills; itching; joint or muscle pain; reddish skin lesions, generally with a purple center; sores, ulcers, or white spots inside the mouth or on the lips; or unusual tiredness or weakness.
Liver problems may occur while you are using this medication. Stop using this medicine and check with your doctor immediately in case you're having more than 1 of the symptoms: abdominal or stomach discomfort or tenderness; claycolored stools; dark urine; reduced appetite; fever; headache; lack of appetite; nausea or vomiting; skin rash; swelling of the feet or lower legs; uncommon tiredness or weakness; or yellow eyes or skin.
Leflunomide may temporarily decrease the amount of white blood cells in your blood, raising the possibility of acquiring disease. Additionally, it may lower the number of platelets, which are necessary for proper blood-clotting. If that occurs, there are certain safeguards you can take, particularly when your blood count is reduced, to decrease the danger of infection or bleeding:
If you can, avoid people with infections. Check with your doctor promptly in the event you believe you are getting disease or if you obtain a fever or chills, cough or hoarseness, lower back or side pain, or unpleasant or difficult urination
Check with your doctor immediately if you notice any unusual bleeding or bruising; black, tarry stools; blood in the urine or stools; or pinpoint red spots in your skin.
Be cautious when working with a normal toothbrush, dental floss, or toothpick. Your medical doctor, dentist, or nurse may recommend additional ways to wash your own teeth and gums. Check to your own medical doctor before having any dental work done.
Don't contact your eyes or the interior of your nose unless you have simply cleaned your hands and have not handled anything else while in the interim,.
Take care not to cut yourself if you are using sharp items for instance a safety razor or fingernail or toenail cutters.
Avoid contact sports or other circumstances where bruising or harm could occur.
Check with your own doctor immediately when you got a cough with or without a temperature, shortness of breathing, or any difficulty with respiration.
Before you start using this medicine you'll need to have a whole skin test for tuberculosis. Tell your doctor if you or anybody in your house has ever had a favorable response to a tuberculosis check.
Using this medication may increase your chance of having severe infections or cancer. Talk to your doctor if you have concerns about this threat.
Do not take other medicines unless they've been discussed with your physician. This consists of prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.
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