Orlistat can be used for managing obesity in overweight adults. It can be used to reduce the risk of weight regain after previous weight loss. It is used together with a reduced-calorie, lowfat diet. Orlistat is a gastrointestinal lipase inhibitor. It functions by blocking the digestion of fats in the diet.
Use Orlistat as instructed by your physician.
Simply take Orlistat by mouth with each food. Do not take more than three capsules daily.
If a meal is missed or contains no-fat, don't take a dose of Orlistat.
Orlistat may decrease your absorption of vitamins. Take a multivitamin once a day at bed-time.
If in addition, you take a thyroid hormone (eg, synthroid), don't take it within 4 hrs before or after taking Orlistat. Check with your physician if you have questions.
Should you also take cyclosporine, do not take it within 2 hrs before or after taking Orlistat. Check with your doctor before you consider Orlistat with cyclosporine.
In the event that you miss a dose of Orlistat, take it when you recall. Continue to take it as instructed by your physician.
Ask your health care provider any questions you might have regarding how to use Orlistat.
Don't use Orlistat if:
you are allergic to any ingredient in Orlistat
you are not overweight
You've got gall-bladder difficulties, bile flow problems (eg, cholestasis), or problems ingesting food (malabsorption).
Contact your physician or doctor immediately if any of these apply to you personally.
Some medical conditions may interact with Orlistat. Tell your doctor or pharmacist if you got any medical conditions, particularly if any of the following apply to you:
In case you are pregnant, planning to get pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
For those who are allergic to medicines, foods, or other materials
When you have an eating disorder (eg, anorexia, bulimia)
In case you have a brief history of gall-bladder, liver, pancreas, or thyroid problems; diabetes; or kidney stones
should you take medication for diabetes or thyroid issues, or when you take any medicines for weight loss
When you have obtained an organ transplant or whenever you take cyclosporine.
Some medicines may interact with Orlistat. Inform your doctor in case you are taking any other medicines, particularly the following:
Anticoagulants (eg, warfarin) because the danger of hemorrhaging may be increased by Orlistat
Amiodarone, cyclosporine, or thyroid hormones (eg, unithroid) because their usefulness may be decreased by Orlistat.
This might not be a whole list of all relationships that might happen. Ask your doctor if Orlistat might interact with several other medicines that you take. Check with your doctor before you begin, stop, or change the dose of any medication.
Important safety tips:
Do NOT take much more than the recommended dose without checking with your physician. Getting more than the recommended dosage may not really help you lose more weight. It could increase your risk of side effects.
Proper diet and exercise are significant in order to lose excess weight and keep it off. Follow the diet and exercise program given to you by your doctor.
Orlistat may cause changes in your bowel or stool (eg, fuel with oily spotting, loose stools, more frequent stools). Consuming a low-fat diet can help reduce these unwanted side effects.
Inform your doctor or dentist that you take Orlistat before you obtain any medical or dental treatments, emergency care, or surgery.
Diabetes patients - Orlistat might change your blood sugar. Check blood sugar carefully. Request your physician before changing the dose of your diabetes medication.
Rarely, some patients using Orlistat have developed severe liver problems. Contact your physician immediately if you have yellowing of the skin or eyes, dark urine, pale stools, unusual weakness, lack of appetite, or serious or persistent nausea.
Orlistat should not be used in children younger 18 years; safety and effectiveness in these children have not been validated.
Pregnancy and breastfeeding: Don't take Orlistat if you're pregnant. In the event you become pregnant, contact your physician. It is not known if Orlistat is found in breast milk. Don't breastfeed while taking Orlistat.

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